Contact Our Spravato Department: 631.813.4950

Eligibility for Spravato may vary per patient. If you are interested in Spravato treatment, ask your provider for more details.

Spravato Treatment

SPRAVATO (esketamine) is a prescription medicine nasal spray, used along with an antidepressant, taken by mouth to treat: Adults with treatment-resistant depression (TRD) Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions. It is a first-of-its kind medicine approved by the FDA in two major depressive disorder (MDD) subpopulations with high unmet need.

If you are interested in Spravato Treatment - Please talk to your provider for eligibility and details.

How It Works

SPRAVATO® is taken with an oral antidepressant

  • You administer SPRAVATO® nasal spray yourself under the supervision of a healthcare provider at a certified SPRAVATO® treatment center

  • SPRAVATO® is taken twice a week for the first four weeks

  • After the first four weeks, you and your doctor will discuss and determine if treatment should be continued and the dose and how often you’ll receive SPRAVATO®

For more information, go to: https://www.spravato.com/taking-spravato

  • How will I take SPRAVATO®?

    You will take SPRAVATO® nasal spray yourself, under the supervision of a healthcare provider in a healthcare setting. Your healthcare provider will show you how to use the SPRAVATO® nasal spray device.

    • Your healthcare provider will tell you how much SPRAVATO® you will take and when you will take it.

    • Follow your SPRAVATO® treatment schedule exactly as your healthcare provider tells you to.

    • During and after each use of the SPRAVATO® nasal spray device, you will be checked by a healthcare provider who will decide when you are ready to leave the healthcare setting.

    • You will need to plan for a caregiver or family member to drive you home after taking SPRAVATO®

    • If you miss a SPRAVATO® treatment, your healthcare provider may change your dose and treatment schedule.

    • Some people taking SPRAVATO® get nausea and vomiting. You should not eat for at least 2 hours before taking SPRAVATO® and not drink liquids at least 30 minutes before taking SPRAVATO®.

    • If you take a nasal corticosteroid or nasal decongestant medicine take these medicines at least 1 hour before taking SPRAVATO®.

  • What are the side effects of Spravato?

    The side effects of Spravato include:

    • Feeling sleepy (sedation)

    • Feeling disconnected from yourself, your thoughts, feelings and things around you (dissociation)

    • Abuse and misuse

    • Increased risk of suicidal thoughts and behavior

    • Temporary increase in blood pressure that may last about four hours after a dose

    • Problems with thinking clearly

    • Bladder problems

    This is a summary of serious side effects for SPRAVATO®. Read the complete information about these serious side effects here.

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